July 10, 2024
Safety, Pharmacokinetics, and Pharmacodynamics of the New Aldose Reductase Inhibitor Govorestat (AT-007) After a Single and Multiple Doses in Participants in a Phase 1/2 Study
Riccardo Perfetti, MD, PhD, Evan Bailey, MD, Stella Wang, MPH, MS, Richard Mills, PhD, Ramon Mohanlal, MD, PhD, MBA, Shoshana Shendelman, PhD
Journal of Clinical Pharmacology
May 4, 2020
Biallelic mutations in SORD cause a common and potentially treatable hereditary neuropathy with implications for diabetes
Andrea Cortese, Yi Zhu, Adriana P. Rebelo, Sara Negri, Steve Courel, Lisa Abreu, Chelsea J. Bacon, Yunhong Bai, Dana M. Bis-Brewer, Enrico Bugiardini, Elena Buglo, Matt C. Danzi, Shawna M. E. Feely, Alkyoni Athanasiou-Fragkouli, Nourelhoda A. Haridy, Inherited Neuropathy Consortium, Rosario Isasi, Alaa Khan, Matilde Laurà, Stefania Magri, Menelaos Pipis, Chiara Pisciotta, Eric Powell, Alexander M. Rossor, Paola Saveri, Janet E. Sowden, Stefano Tozza, Jana Vandrovcova, Julia Dallman, Elena Grignani, Enrico Marchioni, Steven S. Scherer, Beisha Tang, Zhiqiang Lin, Abdullah Al-Ajmi, Rebecca Schüle, Matthis Synofzik, Thierry Maisonobe, Tanya Stojkovic, Michaela Auer-Grumbach, Mohamed A. Abdelhamed, Sherifa A. Hamed, Ruxu Zhang, Fiore Manganelli, Lucio Santoro, Franco Taroni, Davide Pareyson, Henry Houlden, David N. Herrmann, Mary M. Reilly, Michael E. Shy, R. Grace Zhai, Stephan Zuchner
Nature Genetics
April 8, 2024
A Selective Aldose Reductase Inhibitor (AT-001) For the Treatment of Diabetic Cardiomyopathy: Primary Results of the Phase 3 Randomized Controlled ARISE-HF Study
Presented by Riccardo Perfetti, MD, PhD, Chief Medical Officer, Applied Therapeutics
2024 American College of Cardiology Annual Scientific Session
July 9, 2024
Randomized Trial of a Selective Aldose Reductase Inhibitor in Patients with Diabetic Cardiomyopathy
James L. Januzzi, MD, Javed Butler, MD, MPH, MBA, Stefano Del Prato, MD, Justin A. Ezekowitz, MB, BCH, Nasrien E. Ibrahim, MD, MPH, Carolyn S.P. Lam, MBBS, PHD, Gregory D. Lewis, MD, Thomas H. Marwick, MBBS, PHD, MPH, Riccardo Perfetti, MD, PHD, Julio Rosenstock, MD, Scott D. Solomon, MD, W.H. Wilson Tang, MD, Faiez Zannad, MD, PHD
Journal of the American College of Cardiology
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