While most people with SORD Deficiency are diagnosed with mild to moderate symptoms in adolescence or early adulthood, the disease can progress, leading to future challenges, such as gait abnormalities, scoliosis, and hip dysplasia. These challenges can lead to a poor quality of life depending on the severity.

Given the recent identification of SORD Deficiency as a unique hereditary motor neuropathy, further research is needed to improve diagnosis and management.